南阳张发明

⑴ 张氏家谱字辈是怎么排列的

张氏家谱地域字辈排行：

1、安徽省金寨县：启大道，正贤良， 一经传家，宗功世守 ，克承先训，继绪可久，长思祖德，齐敦孝友，尚学自立，光前裕后。

2、安徽省亳州市：学北天守广，德心玉俊良；志明本绍统，兴家传费祥。

3、安徽省桐城市：万志之云永，启世自荣昌，大德应时选，兴朝必以良。

4、山东省齐河县：令之允传方圣永怀修世德。

5、山东省新泰市：广安树继云，凤仙世孝远，仁怀振家真。

6、山东省淄博市：成先志光宗，德士传家法。

7、山东省青岛市：世开黄道日，双德吉祥始。

8、山东省兖州市：文士堂西广，召书庆元祥，承彦明嘉绪，振国守典长。

9、山东省诸城市：甲子寿光来，青春依旧在。

10、河南省郸城县：栋国大怀付得加其太平安。

11、河南省邓州市：明喷文鳯，荣先可绍，一本清传，福泽永继，学定万全。

12、湖南省洞口县山门水口张氏：朝鹤忠龙秀，辅遂臣泌发，福显永良才，时大友之天，锡爵文明起，赐禄华映先，千年宏圣道，万世富崇元，家声绵祖泽，懿德复仙元。

13、湖南省宁乡县：德茂光先祖良贻在克家殷勤敦实务谦厚发菁华绂冕芬徽圭璋品诣嘉席珍留待聘掞藻灿云霞。

14、贵州省：荣诗承奇，仁能洪道，国均先进世，奇忠赵王姖，天远开绵秀，普打郑昌依。

15、江西省赣州市：正元高国福玉定志用金□顺茂盛昌忠信永有光学士攀龙凤贤才振纪刚仁义为珍宝诗书。

16、江西省武宁县：挥公肇远绪，友吉炳成周，善颂钦君子，师臣作汉模，宗演三溪秀，嗣昭六监图。必昌崇有。

17、四川省：世卫国步元昌茂兴龙吉。

18、重庆市：鸿才启世，智胜绍欣；传扬天道，信步乾坤。苍鹰展翅，高远超群；翱翔霄汉，啸傲风云。雄狮过岗，迅猛驰奔；横行原野，威震丛林。狂龙涌浪，广阔无垠；蒸腾甘雨，泽惠黎民。

19、江苏省如皋县：大宗乃敦笃毓秀必诗书常守同居训其昌占庆余。

20、江苏省丰县：国泰民安，田广文光，敬传祖，继中恒。

(1)南阳张发明扩展阅读：

人口分布：

宋朝时期，张姓大约有490万人，约占全国人口的6.3%，为宋朝第三大姓。张姓第一大省是山东省。

在全国的分布，主要集中于山东、河南两省，大约占张姓总人口的27.7%，其次分布于四川、河北、陕西、湖南、湖北、山西、甘肃、江西八省，集中了54.5%。

明朝时期，张姓大约有560万人，约占全国人口6%，为明朝第二大姓。

在全国的分布，主要集中于江苏、浙江、江西三省，大约占全国张姓人口的36%，江苏省成为张姓第一大省。

当代，张姓的人口已达到近8500万，全国第三大姓，大约占全国人口的6.79%。

在全国的分布主要集中河南、山东、河北三省，大约占张姓总人口的27.5%，其次分布于江苏、四川、安徽、辽宁、黑龙江、湖北六省，集中了28.5%。

河南居住了张姓总人口的10.1%，当代张姓第一大省。全国形成以长江为界的高比率的北方张姓区和低比率的南方张姓区。

⑵ 张发明三个字的拼音

张zhāng
发fā
明míng

⑶ 张发明的代表性学术论文

1. Wibowo AS, Singh M, Reeder KM, Carter JJ, Kovach AR, Meng W, Ratnam M, Zhang F, Dann CE . Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15180-8.
2. Rogers T, Li P, Smiley D, DiMarchi RD, and Zhang F., (2007), Design, synthesize and crystallization of a novel glucagon analog as a therapeutic agent. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jul 1;63(Pt 7):599-601.
3. Singh J, Ling L, Sawyer JS, Lee W, Zhang F, Yingling JM., (2005), Successful discovery of TbRI (ALK5) kinase inhibitors using HTS, target-hopping and virtual screening, Chemistry Today, 23 (3): 35-38.
4. Hamdouchi C, Zhong B, Mendoza J, Zhang F et al. (2005), Structure-Based Design of a New Class of Highly Selective Aminoimidazo[1,2-á]pyridine-Based Inhibitors of Cyclin Dependent Kinases, bioorganic & Medicinal Chemistry Letters. 15 (7): 1943-1947.
5. Jaramillo C, Zhang F. et al (2004), Aminoimidazo[1,2-a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation, bioorganic & Medicinal Chemistry Letters. 14(24): 6095-6099.
6. J. Singh, J. Yingling, Zhang F, et al (2004), Transforming the TGF-â pathway: Convergence of distinct lead generation strategies on a novel kinase pharmcophroe for TbRI, Current Opinion in Drug Discovery and Development 7(4): 10-20.
7. Al-Awar RS, Ray JE, Zhang F. etal (2004). Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors. Bioorg Med Chem Lett. 14(15): 3925-3928.
8. Sawyer JS, Beight DW, Zhang F, Yingling JM (2004). Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain. Bioorg Med Chem Lett. 14(13): 3581-3584.
9. Hadouchi C, Keyser H,Zhang F, Brooks H, et al (2004). The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo(1,2-a]pyridines. Molecular Cancer Therapeutics. 3(1):1-9
10. Vincent J.-P, Johnson RB, Parsons S, Zhang F, Wang QM (2003). Identification of a C-terminal regulatory motif in hepatitis C virus RNA-dependent RNA polymerase: structural and biochemical analysis. J. Virology. 77: 9020-9028
11. Sanchez-Martinez C, Shih C, Zhu G, Dempsey JA, Zhang F(2003) . Studies on Cyclin Dependent Kinase Inhibitors:Indolo[2,3-a]pyrrolo[3,4-c]carbazoles versus Bis-indolylmaleimides, Bioorganic & Medicinal Chemistry Letters 13:3841-3846.
12. Vieth M, Brooks H, Hamdouchi C, McMillen W, Sawyer JS, Yingling J, and Zhang F(2003). Combining Medicinal Chemistry with Chemogenomic and Computer-Aided Structure-Based Design in Development of Novel Kinase Inhibitors, Cell. Mol. Biol. Lett 8 (2A):566-567
13. Sawyer JS,Herron DK,Edward CR, Zhang F, and Yingling J (2003). Synthesis and Activity of New Aryl- and Heteroaryl-Substituted Pyrazole Inhibitors of the Transforming Growth Factor-beta Type I Receptor Kinase Domain. Journal of Medicinal Chemistry 46 (19):3953-3956.
14. Wang QM, Hockman M, Staschke K, Zhang F, Parsons S (2002). Oligomerization and Cooperative RNA Synthesis Activity of HCV RNA-Dependent RNA Polymerase, J. Virology. 76:3865-3872
15. Jin L, Briggs S, Clawson D, Schevitz R, Smiley D, Tashjian A, Zhang F (2000). “Crystal Structure of Human Parathyroid Hormone 1-34 at 0.9 Å Resolution”, J. Biol. Chem. 275:27238-27244.
16. Zhang F, Basinski M, DiMarchi RD et al. (1997) “Crystal Structure of the Obese Protein Leptin-E100”, Nature387:206-209
17. Zhang J, Zhang F, Ebert D, Cobb MH, and Goldsmith EJ(1995) “Activity of the MAP Kinase ERK2 is Controlled by a Flexible Surface Loop”, Structure 3:299-307.
18. Zhang F, Strand A, Robbins D, Cobb MH, and Goldsmith EJ (1994) “Crystal Structure of MAP kinase ERK2 at 2.3Å Resolution”. Nature. 367: 704-711.
19. Zhang F, Robbins D, Cobb MH and Goldsmith EJ (1993) “ Crystallization and Preliminary X-ray Studies of Extracellular Signal-regulated Kinase-2/MAP kinase with an Incorporated His-tag”. J. Mol.Biol. 233: 550-552.
20. Lin Z, Li J , Zhang F and Tsou C-L (1993) “Structure of D-Glyceraldehyde-3-phosphate Dehydrogenase from Palinurus Versicolor Carrying the fluorescent NAD Derivatives at 2.7 Å Resolution” Arch. Biochem. Biophy. 302:161-166.
21. Zhang F, Kobe B, Stewart CB, Rutter W and Goldsmith EJ (1991) “ Structural Evolution of an Enzyme Specificity: The Structure of Rat Carboxypeptidase A2 at 1.9 Å Resolution”. J. Biol. Chem. 266: 24606-24612.