南陽張發明

⑴ 張氏家譜字輩是怎麼排列的

張氏家譜地域字輩排行：

1、安徽省金寨縣：啟大道，正賢良， 一經傳家，宗功世守 ，克承先訓，繼緒可久，長思祖德，齊敦孝友，尚學自立，光前裕後。

2、安徽省亳州市：學北天守廣，德心玉俊良；志明本紹統，興家傳費祥。

3、安徽省桐城市：萬志之雲永，啟世自榮昌，大德應時選，興朝必以良。

4、山東省齊河縣：令之允傳方聖永懷修世德。

5、山東省新泰市：廣安樹繼雲，鳳仙世孝遠，仁懷振家真。

6、山東省淄博市：成先志光宗，德士傳家法。

7、山東省青島市：世開黃道日，雙德吉祥始。

8、山東省兗州市：文士堂西廣，召書慶元祥，承彥明嘉緒，振國守典長。

9、山東省諸城市：甲子壽光來，青春依舊在。

10、河南省鄲城縣：棟國大懷付得加其太平安。

11、河南省鄧州市：明噴文鳯，榮先可紹，一本清傳，福澤永繼，學定萬全。

12、湖南省洞口縣山門水口張氏：朝鶴忠龍秀，輔遂臣泌發，福顯永良才，時大友之天，錫爵文明起，賜祿華映先，千年宏聖道，萬世富崇元，家聲綿祖澤，懿德復仙元。

13、湖南省寧鄉縣：德茂光先祖良貽在克家殷勤敦實務謙厚發菁華紱冕芬徽圭璋品詣嘉席珍留待聘掞藻燦雲霞。

14、貴州省：榮詩承奇，仁能洪道，國均先進世，奇忠趙王姖，天遠開綿秀，普打鄭昌依。

15、江西省贛州市：正元高國福玉定志用金□順茂盛昌忠信永有光學士攀龍鳳賢才振紀剛仁義為珍寶詩書。

16、江西省武寧縣：揮公肇遠緒，友吉炳成周，善頌欽君子，師臣作漢模，宗演三溪秀，嗣昭六監圖。必昌崇有。

17、四川省：世衛國步元昌茂興龍吉。

18、重慶市：鴻才啟世，智勝紹欣；傳揚天道，信步乾坤。蒼鷹展翅，高遠超群；翱翔霄漢，嘯傲風雲。雄獅過崗，迅猛馳奔；橫行原野，威震叢林。狂龍涌浪，廣闊無垠；蒸騰甘雨，澤惠黎民。

19、江蘇省如皋縣：大宗乃敦篤毓秀必詩書常守同居訓其昌占慶余。

20、江蘇省豐縣：國泰民安，田廣文光，敬傳祖，繼中恆。

(1)南陽張發明擴展閱讀：

人口分布：

宋朝時期，張姓大約有490萬人，約佔全國人口的6.3%，為宋朝第三大姓。張姓第一大省是山東省。

在全國的分布，主要集中於山東、河南兩省，大約占張姓總人口的27.7%，其次分布於四川、河北、陝西、湖南、湖北、山西、甘肅、江西八省，集中了54.5%。

明朝時期，張姓大約有560萬人，約佔全國人口6%，為明朝第二大姓。

在全國的分布，主要集中於江蘇、浙江、江西三省，大約佔全國張姓人口的36%，江蘇省成為張姓第一大省。

當代，張姓的人口已達到近8500萬，全國第三大姓，大約佔全國人口的6.79%。

在全國的分布主要集中河南、山東、河北三省，大約占張姓總人口的27.5%，其次分布於江蘇、四川、安徽、遼寧、黑龍江、湖北六省，集中了28.5%。

河南居住了張姓總人口的10.1%，當代張姓第一大省。全國形成以長江為界的高比率的北方張姓區和低比率的南方張姓區。

⑵ 張發明三個字的拼音

張zhāng
發fā
明míng

⑶ 張發明的代表性學術論文

1. Wibowo AS, Singh M, Reeder KM, Carter JJ, Kovach AR, Meng W, Ratnam M, Zhang F, Dann CE . Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15180-8.
2. Rogers T, Li P, Smiley D, DiMarchi RD, and Zhang F., (2007), Design, synthesize and crystallization of a novel glucagon analog as a therapeutic agent. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jul 1;63(Pt 7):599-601.
3. Singh J, Ling L, Sawyer JS, Lee W, Zhang F, Yingling JM., (2005), Successful discovery of TbRI (ALK5) kinase inhibitors using HTS, target-hopping and virtual screening, Chemistry Today, 23 (3): 35-38.
4. Hamdouchi C, Zhong B, Mendoza J, Zhang F et al. (2005), Structure-Based Design of a New Class of Highly Selective Aminoimidazo[1,2-á]pyridine-Based Inhibitors of Cyclin Dependent Kinases, bioorganic & Medicinal Chemistry Letters. 15 (7): 1943-1947.
5. Jaramillo C, Zhang F. et al (2004), Aminoimidazo[1,2-a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation, bioorganic & Medicinal Chemistry Letters. 14(24): 6095-6099.
6. J. Singh, J. Yingling, Zhang F, et al (2004), Transforming the TGF-â pathway: Convergence of distinct lead generation strategies on a novel kinase pharmcophroe for TbRI, Current Opinion in Drug Discovery and Development 7(4): 10-20.
7. Al-Awar RS, Ray JE, Zhang F. etal (2004). Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors. Bioorg Med Chem Lett. 14(15): 3925-3928.
8. Sawyer JS, Beight DW, Zhang F, Yingling JM (2004). Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain. Bioorg Med Chem Lett. 14(13): 3581-3584.
9. Hadouchi C, Keyser H,Zhang F, Brooks H, et al (2004). The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo(1,2-a]pyridines. Molecular Cancer Therapeutics. 3(1):1-9
10. Vincent J.-P, Johnson RB, Parsons S, Zhang F, Wang QM (2003). Identification of a C-terminal regulatory motif in hepatitis C virus RNA-dependent RNA polymerase: structural and biochemical analysis. J. Virology. 77: 9020-9028
11. Sanchez-Martinez C, Shih C, Zhu G, Dempsey JA, Zhang F(2003) . Studies on Cyclin Dependent Kinase Inhibitors:Indolo[2,3-a]pyrrolo[3,4-c]carbazoles versus Bis-indolylmaleimides, Bioorganic & Medicinal Chemistry Letters 13:3841-3846.
12. Vieth M, Brooks H, Hamdouchi C, McMillen W, Sawyer JS, Yingling J, and Zhang F(2003). Combining Medicinal Chemistry with Chemogenomic and Computer-Aided Structure-Based Design in Development of Novel Kinase Inhibitors, Cell. Mol. Biol. Lett 8 (2A):566-567
13. Sawyer JS,Herron DK,Edward CR, Zhang F, and Yingling J (2003). Synthesis and Activity of New Aryl- and Heteroaryl-Substituted Pyrazole Inhibitors of the Transforming Growth Factor-beta Type I Receptor Kinase Domain. Journal of Medicinal Chemistry 46 (19):3953-3956.
14. Wang QM, Hockman M, Staschke K, Zhang F, Parsons S (2002). Oligomerization and Cooperative RNA Synthesis Activity of HCV RNA-Dependent RNA Polymerase, J. Virology. 76:3865-3872
15. Jin L, Briggs S, Clawson D, Schevitz R, Smiley D, Tashjian A, Zhang F (2000). 「Crystal Structure of Human Parathyroid Hormone 1-34 at 0.9 Å Resolution」, J. Biol. Chem. 275:27238-27244.
16. Zhang F, Basinski M, DiMarchi RD et al. (1997) 「Crystal Structure of the Obese Protein Leptin-E100」, Nature387:206-209
17. Zhang J, Zhang F, Ebert D, Cobb MH, and Goldsmith EJ(1995) 「Activity of the MAP Kinase ERK2 is Controlled by a Flexible Surface Loop」, Structure 3:299-307.
18. Zhang F, Strand A, Robbins D, Cobb MH, and Goldsmith EJ (1994) 「Crystal Structure of MAP kinase ERK2 at 2.3Å Resolution」. Nature. 367: 704-711.
19. Zhang F, Robbins D, Cobb MH and Goldsmith EJ (1993) 「 Crystallization and Preliminary X-ray Studies of Extracellular Signal-regulated Kinase-2/MAP kinase with an Incorporated His-tag」. J. Mol.Biol. 233: 550-552.
20. Lin Z, Li J , Zhang F and Tsou C-L (1993) 「Structure of D-Glyceraldehyde-3-phosphate Dehydrogenase from Palinurus Versicolor Carrying the fluorescent NAD Derivatives at 2.7 Å Resolution」 Arch. Biochem. Biophy. 302:161-166.
21. Zhang F, Kobe B, Stewart CB, Rutter W and Goldsmith EJ (1991) 「 Structural Evolution of an Enzyme Specificity: The Structure of Rat Carboxypeptidase A2 at 1.9 Å Resolution」. J. Biol. Chem. 266: 24606-24612.